The Reds hoped to end the regular season second in the East and claim an all-important first-round bye in the Audi MLS Cup Playoffs.
The Portland Timbers traveled to Vancouver with hopes to capture the Cascadia Cup.
Orlando City looked to claw their way back into the Eastern Conference Playoff picture as they hosted the visiting Montreal Impact.
Vancouver and Seattle met in a Cascadia Cup matchup,
Both the Philadelphia Union and Toronto FC looked to grab points at BMO Field.